N-Boc-2-Piperidone is a versatile protected piperidone intermediate widely used in pharmaceutical research, medicinal chemistry, organic synthesis, and the development of Active Pharmaceutical Ingredient (API) intermedi…
N-Boc-2-Piperidone is a versatile protected piperidone intermediate widely used in pharmaceutical research, medicinal chemistry, organic synthesis, and the development of Active Pharmaceutical Ingredient (API) intermediates. Chemically known as tert-Butyl 2-Oxopiperidine-1-Carboxylate, it contains a six-membered piperidone ring protected at the nitrogen atom with a tert-butoxycarbonyl (Boc) group. This protected structure provides useful synthetic flexibility and makes the compound an important building block for multi-step pharmaceutical and fine-chemical synthesis.
N-Boc-2-Piperidone is particularly useful in synthetic routes requiring controlled modification of the piperidone ring or subsequent removal of the Boc protecting group. It can participate in a variety of organic transformations and is therefore valuable for medicinal chemistry programs, route development, process optimization, and preparation of more advanced nitrogen-containing pharmaceutical intermediates. Its combination of a protected nitrogen atom and cyclic ketone functionality allows further selective chemical transformations.
NEXA IMPEX supplies N-Boc-2-Piperidone to pharmaceutical manufacturers, research laboratories, contract research organizations (CROs), contract development and manufacturing organizations (CDMOs), and specialty chemical companies. The product can be supplied in laboratory, development, and commercial quantities with appropriate packaging and technical documentation according to customer requirements.
NEXA IMPEX focuses on consistent product quality, reliable supply, controlled handling, and technical documentation support. COA, MSDS/SDS, product specifications, TDS, and applicable analytical documentation can be provided according to the agreed product specification, supporting customers in pharmaceutical research, process development, medicinal chemistry, and commercial intermediate sourcing.
NEXA IMPEX supplies N-Boc-2-Piperidone in laboratory, development, and commercial quantities. Standard packaging may include 100 g, 500 g, 1 kg, 5 kg, 10 kg, and 25 kg, with customized packaging available according to customer requirements. Suitable sealed packaging is used to help maintain product quality during storage and transportation.
Reference specification for 1-Boc-2-Piperidone — confirm current certificate of analysis against your target pharmacopoeia at enquiry.
| Parameter | Specification |
|---|---|
| Molecular Formula | C₁₀H₁₇NO₃ |
| Molecular Weight | 199.25 g/mol |
| Assay (GC) | NLT 97.0% |
| Melting Point | 29–36°C |
| Storage | Store tightly closed in a dry place |
Common questions from buyers evaluating 1-Boc-2-Piperidone sourcing from NexaImpex.