NEXAIMPEX
1,4-Benzodioxan-2-Carboxylic Acid is a specialized aromatic heterocyclic compound used in organic synthesis and chemical research. Its structure combines a benzene-fused 1,4-dioxane ring with a carboxylic acid group, pr…
1,4-Benzodioxan-2-Carboxylic Acid is a specialized aromatic heterocyclic compound used in organic synthesis and chemical research. Its structure combines a benzene-fused 1,4-dioxane ring with a carboxylic acid group, providing a useful combination of aromatic, ether, and acidic functionalities. These structural characteristics make the compound relevant to researchers developing new substituted heterocyclic molecules and specialty organic intermediates.
The benzodioxane framework is an important structural motif encountered in medicinal chemistry and pharmaceutical research. Accordingly, 1,4-Benzodioxan-2-Carboxylic Acid can serve as a useful starting material or intermediate for synthetic programs in which the benzodioxane nucleus needs to be retained or further functionalized. Its carboxylic acid group provides a convenient reactive site for transformations such as esterification, amidation, and other conventional organic reactions, subject to the requirements of the particular synthetic route.
The product is particularly suitable for research and development, organic synthesis, pharmaceutical intermediate development, medicinal chemistry, and specialty chemical manufacturing. Researchers may use this material for the preparation of derivatives with modified functional groups or for exploring structure–activity relationships in compounds containing the benzodioxane structural motif.
From a procurement and quality perspective, 1,4-Benzodioxan-2-Carboxylic Acid is available as a solid chemical material. TCI specifies a white to almost-white powder-to-crystal appearance and a minimum purity of 98.0%, while Sigma-Aldrich lists a 97% grade and reports a solid form with a literature melting point of approximately 126–130°C. These differences demonstrate why the final website specification should be aligned with the actual batch CoA being supplied.
The compound has a molecular weight of 180.16 g/mol, allowing it to be readily characterized using standard analytical techniques. Identification and quality assessment can include chromatographic purity, neutralization titration, melting point, spectroscopic identification, and other analytical tests according to the customer's requirements. TCI specifically lists both GC purity and neutralization-titration purity specifications for its reference material.
For commercial supply, Nexaimpex can position 1,4-Benzodioxan-2-Carboxylic Acid as a specialty organic chemical and pharmaceutical/chemical synthesis intermediate, rather than as a finished API. The product can be offered for laboratory, research, process-development, and commercial synthesis requirements, subject to availability and agreed specifications.
It is also important to distinguish the general product from its stereochemically defined forms. The general material associated with CAS 3663-80-7 is listed by PubChem and NIST, whereas (R)-1,4-Benzodioxane-2-carboxylic acid is separately identified with CAS 70918-53-5. Therefore, customers requiring a specific enantiomer should clearly state the stereochemical requirement when requesting a quotation or product specification.
1,4-Benzodioxan-2-Carboxylic Acid can be supplied in suitable packaging according to customer quantity, handling requirements, storage conditions, transportation requirements, and intended application. Packaging can be arranged for laboratory, R&D, pilot-scale, and commercial requirements.
Reference specification for 1,4-Benzodioxan-2-Carboxylic Acid — confirm current certificate of analysis against your target pharmacopoeia at enquiry.
| Parameter | Specification |
|---|---|
| Molecular Formula | C₉H₈O₄ |
| Molecular Weight | 180.16 g/mol |
| Physical State | Solid |
| Purity by GC | Min. 98.0% |
| Purity by Neutralization Titration | Min. 98.0% |
| Melting Point | 124–128°C |
| StorageStorage | Room Temperature; Cool and Dark Place, <15°C Recommended |
Common questions from buyers evaluating 1,4-Benzodioxan-2-Carboxylic Acid sourcing from NexaImpex.